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This research was supported in part by the National Heart, Lung, and Blood Institute, United States (grant 5T32HL0098036 to E.A.A.). The University of Pittsburgh, United States holds a Physician-Scientist Institutional Award from the Burroughs Wellcome Fund (to E.A.A.).
Author conflict of interest: none.
The editors and reviewers of this article have no relevant financial relationships to disclose per the Journal policy that requires reviewers to decline review of any manuscript for which they may have a conflict of interest.